Treatments for Erectile Dysfunction

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There are many different factors, both physical and psychological, that can cause erectile dysfunction, and some are signs of serious medical conditions.  That’s why it’s important to consult a doctor if you are experiencing ED.

Once you’ve consulted a doctor, they will recommend treatments that will be effective for your specific condition.

Treatment Options

The degree of patient satisfaction shown for some treatments is based on the Comprehensive ED Impact Survey.  The charts below use the following key:

 

Changing Medications  

Patient Satisfaction: Medication Changes

Certain medications may cause or contribute to ED (see our article, “Causes of Erectile Dysfunction“).  You doctor may be able to prescribe alternate medications that alleviate the effect.

Counseling

Patient Satisfaction: Counseling

Coaching or therapy may overcome psychological causes of erectile dysfunction.  It can also be helpful to deal with issues of self-esteem or relationship problems resulting from ED.  See our article, “Counseling for Erectile Dysfunction.”

Electrical Stimulation* 

Direct electrical stimulation with a TENS or similar device may promote regeneration of blood vessels and muscles that are necessary for erections.  However, there is no clinical evidence that supports this as an effective treatment for erectile dysfunction.

intracavernous injections (ICI)

See Penile Injections.

Kegel Exercises

There is some evidence that exercises designed to strengthen the pelvic floor muscles can improve erectile function1.  Kegel exercises are also an excellent way to treat urinary incontinence.

Lifestyle changes

Patient Satisfaction: Lifestyle Changes

Circulatory problems are a very common cause of erectile dysfunction, especially in older men.  Lifestyle changes can improve circulation, though making these changes requires a major commitment.  Lifestyle changes may increase the effectiveness of other treatments, and have the added benefit of improving your overall health.

Changes to consider include:

  • Eating foods that are rich in nitrates, to increase nitric oxide (NO) levels.  Examples include leafy green vegetables, beets, celery, citrus fruits, blueberries, pomegranates, and raw dark chocolate.  You should limit meat, and follow a heart healthy or Mediterranean diet.
  • Exercising, particularly cardiovascular exercise
  • Limiting alcohol consumption
  • Losing weight
  • Stopping smoking

Some patients find that changes to their lifestyle do not give the degree of improvement they expect.  Also, many men have difficulty sticking with the changes.

Herbal Supplements

Patient Satisfaction: Herbal Supplements

Supplements may help with minor cases of ED caused by circulatory problems.  However, they are not very effective, and there are a number of risk factors.  See our article, “Herbal Remedies for Erectile Dysfunction.”

Oral medications (PDE5 Inhibitors)

Patient Satisfaction: Oral Medications

Sildenafil (Viagra), tadalafil (Cialis), vardenafil (Levitra), and avanafil (Stendra) inhibit PDE5.  This helps trap blood in the penis, resulting in firmer erections.

Oral medications are most effective for mild to moderate cases of ED.  Some men dislike the lack of spontaneity when using oral medications.

Penile Implants

A penile implant consists of inflatable chambers inserted in the penis, replacing the corpora cavernosa.  A small pump in the scrotum inflates the chamber, producing an erection. They may be the only viable treatment for men with server ED.  See our article, “Penile Implants.”

Although many men are intimidated by the thought of surgery on the penis, implants have the highest rate of patient satisfaction of any ED treatment, typically over 90%2 3.

Penile Injections

Patient Satisfaction: Penile Injections

Also called intracavernosal injection (ICI) therapy.  Injections of drugs (typically called Bimix, Trimix, or Papaverine) directly into the penis can trigger the chemical signals that inflate the corpora cavernosa, and trap the blood in the penis.  Trimix contains a drug called alprostadil, which needs to be refrigerated.  The drug mix is prescribed by a urologist, who shows the patient how to perform the injection, using a very fine needle.

This is not a good treatment option for men who have difficulty controlling their hands due to neural issues or arthritis.  Injections should not be combined with oral medications.

Penile Suppositories

Patient Satisfaction: Penile Suppositories

Suppositories use the same active chemicals as Penile Injections.  However, rather than being injected, a small suppository is inserted into the urethra.

Penile Surgery

Surgery may be used to clear blocked arteries in the penis, or to repair a venous leak.  Surgery can be a very good option for some men, but it is only useful for very specific conditions.

Penis Pumps (Vacuum Pumps)

Patient Satisfaction: Vacuum Pumps

A penis pump is a plastic tube that fits over the penis.  A pump draws the air out of the sleeve, causing the penis to inflate with blood.  A constriction band is then used to trap the blood in the penis.

Penis pumps can be effective if you have circulatory problems or nerve damage, but many men find them uncomfortable of painful.

Platelet-Rich Plasma (PRP) Injection Therapy*

A one-time PRP injection may stimulate nerve regeneration.  In a preliminary study, PRP injections have improved erectile function when used in conjunction with vacuum pumps and oral medications4.

Shockwave Therapy*

Ultrasonic shockwaves are administered to the penis, over a course of 6-12 sessions, to promote the formation of new blood vessels5.

Stem Cell Therapy*

Stem cells are harvested from the fatty tissue in the patient’s body, and injected into the penis.  The therapy increases the production of nitric oxide (NO)6.  Early studies have shown that many patients regain normal, spontaneous erectile function, and that the improvements are still present a year after the procedure.

Testosterone Therapy

Patient Satisfaction: Testosterone Replacement

Drugs to increase testosterone may be used if the patient has a Testosterone deficiency.

Testosterone increases libido (sexual desire), and also plays an important role in the erection process.

Vitamins

Specific vitamins may be administered if the patient has a vitamin deficiency that is causing or contributing to ED.

*  New or experimental therapies.  This means that:

  • The treatment has not yet been proven to be effective in a large-scale clinical trial.
  • The treatment may have unknown side-effects or risks.
  • The treatment may not be covered by insurance.

New treatments may be a good option, but you should discuss potential drawbacks carefully with your doctor.


References

  1. Dorey, G.; Speakman, M.J.; Feneley, R. C.; Swinkels, A., Dunn, C. D. “Pelvic Floor Exercises for Erectile Dysfunction.” BJU International. Sep 2005; 96(4):595-7. <https://www.ncbi.nlm.nih.gov/pubmed/16104916>
  2. Levine, Laurence A; Estrada, Carlos R; Morgentaler, Abraham. “Mechanical Reliability and Safety of, and Patient Satisfaction with the Ambicor Inflatable Penile Prosthesis: Results of a 2 Center Study.” The Journal of Urology, Sep 2001, Volume 166, Issue 3, pp 932–937. <http://www.jurology.com/article/S0022-5347(05)65867-3/abstract>
  3. Ji, Yoon Seob; Ko,Young Hwii; Song, Phil Hyun; Moon, Ki Hak. “Long-Term Survival and Patient Satisfaction with Inflatable Penile Prosthesis for the Treatment of Erectile Dysfunction.” Korean Journal of Urology. Jun 2015; 56(6):461-465. <https://synapse.koreamed.org/DOIx.php?id=10.4111/kju.2015.56.6.461>
  4. Banno, Joseph J.; Kinnick, Tyson; Roy, Lisbeth; Perito, Paul P.; Antonini, Gabriele; Banno, Daniella. “The Efficacy of Platelet-Rich Plasma (PRP) as a Supplemental Therapy for the Treatment of Erectile Dysfunction (ED): Initial Outcomes.” Sexual Medicine Society of North America Fall Meeting. 3 Nov 2016. <http://www.smsna.org/scottsdale2016/posters/view.php?pid=146>
  5. Gruenwald, Ilan; Appel, Boaz; Kitrey, Noam D.; Vardi, Yoram. “Shockwave Treatment of Erectile Dysfunction.” Therapeutic Advances in Urology. Apr 2013 5(2): 95–99. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607492/>
  6. Reed-Maldonado, Amanda B.; Lue, Tom F. “The Current Status of Stem-Cell Therapy in Erectile Dysfunction: A Review.” The World Journal of Men’s Health. Dec 2016: 34(3): 155–164. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209555/>

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