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Medications That Can Cause Erection Dysfunction

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Many prescription drugs have been linked to erectile dysfunction. If you are taking one of these medications, and experiencing ED, talk to your doctor to see if there is an alternate medication that you could try.

Types of drugs that can cause ED include:

Erectile dysfunction can also be caused by abuse of non-prescription drugs, including alcohol, amphetamines, barbiturates, cocaine, marijuana, methadone, nicotine, and opiates.

Antidepressants, Anti-Anxiety, and Anti-Epileptic Drugs

Amitriptyline (Elavil)

Amoxipine (Asendin)

Buspirone (Buspar)

Chlordiazepoxide (Librium)

Citalopram (Celexa)

Clomipramine (Anafranil)

Clorazepate (Tranxene)

Desipramine (Norpramin)

Diazepam (Valium)

Doxepin (Sinequan)

Duloxetine (Cymbalta)

Escitalopram (Lexapro)

Fluoxetine (Prozac)

Imipramine (Tofranil)

Isocarboxazid (Marplan)

Lorazepam (Ativan)

Nortriptyline (Pamelor)

Oxazepam (Serax)

Paroxetine (Paxil, Pexeva)

Phenelzine (Nardil)

Phenytoin (Dilantin)

Propranodol (Inderal, Innopran XL)

Sertraline (Zoloft)

Tranylcypromine (Parnate)

Venlafaxine (Effexor XR, Vencarm)

Low Risk Medications

There are a small number of Antidepressant drugs that have been found to have a low risk of sexual side-effects:

  • Bupropion (Wellbutrin XL, Wellbutrin SR)
  • Mirtazapine (Remeron)
  • Vilazodone (Viibryd)
  • Vortioxetine (Trintellix)

Antihistamines

Cetirizine

Cimetidine (Tagamet)

Dimehydrinate (Dramamine)

Diphenhydramine (Benadryl)

Hydroxyzine (Vistaril)

Meclizine (Antivert)

Nizatidine (Axid)

Promethazine (Phenergan)

Ranitidine (Zantac)

Antipsychotics

Haloperidol

Olanzapine

Quetiapine

Risperidone

Chemotherapy

Antiandrogens (Casodex, Flutamide, Nilutamide)

Busulfan (Myleran)

Cyclophosphamide (Cytoxan)

Ketoconazole

LHRH agonists (Lupron, Zoladex)

High Blood Pressure Drugs and Diuretics

Atenolol (Tenormin)

Bethanidine

Bisoprolol

Bumetanide (Bumex)

Captopril (Capoten)

Captopril (Capoten)

Chlorothiazide (Diuril)

Chlorthalidone (Hygroton)

Clonidine (Catapres)

Enalapril (Vasotec)

Furosemide (Lasix)

Guanabenz (Wytensin)

Guanethidine (Ismelin)

Guanfacine (Tenex)

Hydralazine (Apresoline)

Hydrochlorothiazide (Esidrix, HydroDIURIL, Hydropres, Inderide, Moduretic, Oretic, Lotensin)

Labetalol (Normodyne)

Methyldopa (Aldomet)

Metoprolol (Lopressor)

Nifedipine (Adalat, Procardia)

Phenoxybenzamine (Dibenzyline)

Prazosin (Minipress)

Propranolol (Inderal)

Reserpine (Serpasil)

Spironolactone (Aldactone)

Triamterene (Maxide, Dyazide)

Verapamil (Calan, Isoptin, Verelan)

Histamine Blockers

Cimetidine (Tagamet)

Nizatidine (Axid)

Ranitidine (Zantac)

Muscle Relaxants

Cyclobenzaprine (Flexeril)

Orphenadrine (Norflex)

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Indomethacin (Indocin)

Naproxen (Anaprox, Naprelan, Naprosyn)

Pain Medications

Opioid pain medications have been linked to lowered levels of testosterone.  If your doctor prescribes an opioid, ask them to test your testosterone level.

Codeine (generic)

Fentanyl (Actiq, Duragesic, Fentora, Abstral, Onsolis)

Hydrocodone (Hysingla, Zohydro ER)

Hydrocodone/Acetaminophen (Lorcet, Lortab, Norco, Vicodin)

Hydromorphone (Dilaudid, Exalgo)

Meperidine (Demerol)

Methadone (Dolophine, Methadose)

Morphine (Kadian, MS Contin, Morphabond)

Oxycodone (OxyContin, Oxaydo)

Oxycodone and Acetaminophen (Percocet, Roxicet)

Oxycodone and Naloxone

Parkinson’s Disease Drugs

Benztropine (Cogentin)

Biperiden (Akineton)

Bromocriptine (Parlodel)

Gabapentin

Levodopa (Sinemet)Procyclidine (Kemadrin)

Trihexyphenidyl (Artane)

Prostate Cancer Drugs

Flutamide (Eulexin)

Leuprolide (Lupron)

Selective Serotonin Reuptake Inhibitors (SSRIs)

Citalopram (Celexa)

Escitalopram (Lexapro)

Fluoxetine (Prozac)

Fluvoxamine (Luvox)

Paroxetine (Paxil)

Sertraline (Zoloft)

Vortioxetine (Trintellix, formerly called Brintellix).

Other Drugs

Finasteride (Proscar and Propecia) – used to treat baldness

Metformin – used to treat high blood sugar due to diabetes

Minoxidil (Rogaine) – used to treat baldness

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