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DHEA and the Treatment of Erectile Dysfunction


Many men are aware that low testosterone – the “male hormone” – can be a possible cause of erectile dysfunction, and that Testosterone Replacement Therapy (TRT) may be effective in restoring erectile dysfunction. However, men may not be aware of dehydroepiandrosterone (DHEA), a weaker male hormone.

Small studies1 2 have shown that DHEA can fight erectile dysfunction.

In addition to fighting erectile dysfunction, DHEA has been shown3 to increase testosterone levels.

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  1. Reiter, W J; Pycha, A; Schatzl, G; Pokorny, A; Gruber, D M; Huber, J C; Marberger, M. “Dehydroepiandrosterone in the treatment of erectile dysfunction: a prospective, double-blind, randomized, placebo-controlled study.” Urology. March 1999; ;53(3):590-4. <>
  2. El-Sakka, Ahmed I. “Dehydroepiandrosterone and Erectile Function: A Review.” World Journal of Men’s Health. September 2018; 36(3): 183–191.
  3. Li, Yuanyuan; Ren, Jie; Li, Na; Liu, Jie; Tan, Shing Cheng; Low, Teck Yew; Ma, Zhimin. “A dose-response and meta-analysis of dehydroepiandrosterone (DHEA) supplementation on testosterone levels: perinatal prediction of randomized clinical trials.” Experimental Gerontology. November 2020; Volume 141. <>

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